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Subway Italian Herbs & Cheese Bread

High histamine

This bread is high in histamine because it is topped with aged cheddar over a wheat and yeast loaf.

Food here is usually assembled to order from components that were prepped earlier in the day, so it tends to be fresher than a drive-through and less fresh than cooking at home. Histamine builds up as protein foods sit, so how long the chicken or beef has been in the warmer matters as much as what is in the bowl. Treat the rating above as a starting point.

It is an herbed loaf of wheat flour, yeast, salt, monterey jack and cheddar cheese, oregano, basil, and garlic.

  • Cheddar cheese — cheddar is aged, and aging lets histamine build up, making it the main driver baked onto this bread.

  • Monterey jack and the base — the jack cheese is a moderate driver, while the wheat flour and yeast sit at moderate too. The herbs and garlic are minor by comparison.

The cheese topping is what lifts this above a plain loaf, so a bread without it lands lower.

This rating comes from Subway's own published ingredient statement, read on August 10, 2026. Restaurant recipes vary by location and change over time, so always check the current listing: source 1, source 2. How we rate foods →

Subway Italian Herbs & Cheese Bread and Subway are trademarks of their respective owners. This page is an independent histamine reference and is not affiliated with, endorsed by, or sponsored by the brand.

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References

  1. SIGHI Food Compatibility List — SIGHI (2026)
  2. Histamine and histamine intolerance — Maintz & Novak (2007)
  3. Histamine Intolerance: The Current State of the Art — Comas-Basté et al. (2020)
  4. Low-Histamine Diets: Is the Exclusion of Foods Justified by Their Histamine Content? — Sánchez-Pérez et al. (2021)
  5. Histamine Intolerance: Symptoms, Diagnosis, and Beyond — Jochum (2024)
  6. Guideline on management of suspected adverse reactions to ingested histamine — Reese et al. (2021)