Papa Murphy's Gluten Free Crust
This crust is moderate, driven by the yeast used to leaven it.
This is sold raw and you bake it at home, which is the freshest case on this whole list. Nothing sits in a warmer, and you control how long it waits between the shop and the oven. Refrigerate it as soon as you get home and bake it the same day, because histamine builds up as protein foods sit whether that happens in a kitchen or in your fridge.
Papa Murphy's Gluten Free Crust rates moderate on histamine, and the yeast used to raise it is what puts it there. Being gluten free does not make it low: gluten and histamine are separate issues, and the leavening is the piece that matters here.
Why papa murphy's gluten free crust is rated moderate
People are often surprised that a fresh, unfermented crust gets flagged at all. Nothing in this base is aged or cured, and the bulk of it is quiet: water, tapioca starch, brown rice flour, canola and sunflower oils, cane sugar, tapioca syrup, salt, and xanthan gum are all starches, fats, and simple additions with very little protein for bacteria to act on. The egg white is the one protein and it is mild. What lifts the crust into the moderate band is the yeast. Baker's yeast raising a dough is not the same thing as a long fermentation, but yeast-risen baked goods are a well-known trigger for people with histamine intolerance, and yeast sits at moderate on this index. That makes the crust a moderate floor for whatever gets built on top of it.
What changes your risk
- Yeast is the lever — the leavening yeast is the single component that sets this crust at moderate. Take yeast out of the picture and the remaining base ingredients are mild.
- Baking does not undo it — heat kills bacteria but does not remove histamine that is already present, so a fully baked crust carries the same moderate note as an unbaked one.
- The base is mostly starch — tapioca starch, brown rice flour, and the oils are low-protein, so a crust sitting out is a texture question rather than a histamine one.
- Toppings decide the rest — the crust sets the floor, and everything added on top moves the finished pizza up or leaves it where it is. Protein toppings are also the part that cares about warm holding, not the crust.
- Reactions to yeast are individual — some people with histamine intolerance notice yeast-risen baked goods clearly and others tolerate them without trouble. That variation is normal in the moderate band.
Lower-histamine alternatives
Papa Murphy's does not have a lower-histamine crust on the list, so there is no straight swap for this one. The items rated lower at Papa Murphy's are Chicken, Onion Mix, and Zesty Herb Blend, and all three are toppings rather than bases. If you are building around a moderate crust, those are the components that will not push the finished pizza higher.
How to lower the risk
Since this is a build-to-order counter, the practical lever is what goes on top rather than what the crust is. Chicken, Onion Mix, and Zesty Herb Blend are the lower-rated components available, so leaning on those keeps the rest of the build from stacking on top of the crust's moderate note. Do not read the gluten free label as a histamine label: it tells you about wheat, not about yeast. If yeast-risen baked goods are something you already know you react to, the crust is the part of this order you cannot work around.
Common questions
Is yeast high in histamine?
Baker's yeast used to leaven a dough is not the same as a long ferment, and it sits at moderate rather than high. It is still one of the more commonly reported triggers among people with histamine intolerance.
Does gluten free mean lower in histamine?
No. Gluten intolerance and histamine intolerance are unrelated, and this crust is rated moderate for its yeast, not for its flour.
Does baking the crust lower the histamine?
No. Baking kills bacteria but does not remove histamine that has already formed, so heat does not change the crust's rating.
What is lower in histamine at Papa Murphy's?
Chicken, Onion Mix, and Zesty Herb Blend are the lower-rated items. None of them is a crust, so they help with the toppings rather than replacing the base.
This rating comes from Papa Murphy's own published ingredient statement, read on August 10, 2026. Restaurant recipes vary by location and change over time, so always check the current listing: source 1, source 2. How we rate foods →
Papa Murphy's Gluten Free Crust and Papa Murphy's are trademarks of their respective owners. This page is an independent histamine reference and is not affiliated with, endorsed by, or sponsored by the brand.
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For educational purposes only. Not medical advice. Consult a healthcare professional for personal guidance.
References
- SIGHI Food Compatibility List — SIGHI (2026)
- Histamine and histamine intolerance — Maintz & Novak (2007)
- Histamine Intolerance: The Current State of the Art — Comas-Basté et al. (2020)
- Low-Histamine Diets: Is the Exclusion of Foods Justified by Their Histamine Content? — Sánchez-Pérez et al. (2021)
- Histamine Intolerance: Symptoms, Diagnosis, and Beyond — Jochum (2024)
- Guideline on management of suspected adverse reactions to ingested histamine — Reese et al. (2021)