Is Papa Murphy's Buffalo Sauce High in Histamine?

Papa Murphy's Buffalo Sauce

High histamine

This buffalo sauce is high in histamine, mainly from the aged cayenne peppers and vinegar.

This is sold raw and you bake it at home, which is the freshest case on this whole list. Nothing sits in a warmer, and you control how long it waits between the shop and the oven. Refrigerate it as soon as you get home and bake it the same day, because histamine builds up as protein foods sit whether that happens in a kitchen or in your fridge.

Histamine Liberator

This is a tangy hot sauce made from distilled vinegar, aged cayenne red peppers, paprika, and garlic.

Aged cayenne peppers lead it — the peppers are aged before use, and that aging builds histamine, which sets the sauce high.
Vinegar and paprika add on — the vinegar base and paprika each keep the level up, so there is no clean way to bring this particular sauce down.

If you want something milder on the same menu, the olive oil blend or garlic butter is a gentler base.

This rating comes from Papa Murphy's own published ingredient statement, read on August 10, 2026. Restaurant recipes vary by location and change over time, so always check the current listing: source 1, source 2. How we rate foods →

Papa Murphy's Buffalo Sauce and Papa Murphy's are trademarks of their respective owners. This page is an independent histamine reference and is not affiliated with, endorsed by, or sponsored by the brand.