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Papa Murphy's Meatballs

High histamine

These meatballs are high in histamine, driven by textured soy protein concentrate and romano cheese.

This is sold raw and you bake it at home, which is the freshest case on this whole list. Nothing sits in a warmer, and you control how long it waits between the shop and the oven. Refrigerate it as soon as you get home and bake it the same day, because histamine builds up as protein foods sit whether that happens in a kitchen or in your fridge.

This topping is beef and meatballs mixed with textured soy protein concentrate, eggs, romano cheese, and spices.

  • Textured soy protein concentrate — this processed soy runs high, and it is a core part of the mix, so it pushes the whole topping up on its own.

  • Romano cheese — romano is an aged, hard cheese, and aging is exactly what builds histamine, so it lands high too, with the meatballs themselves sitting at moderate.

A fresh-meat or veggie topping would be a friendlier choice on the same menu.

This rating comes from Papa Murphy's own published ingredient statement, read on August 10, 2026. Restaurant recipes vary by location and change over time, so always check the current listing: source 1, source 2. How we rate foods →

Papa Murphy's Meatballs and Papa Murphy's are trademarks of their respective owners. This page is an independent histamine reference and is not affiliated with, endorsed by, or sponsored by the brand.

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References

  1. SIGHI Food Compatibility List — SIGHI (2026)
  2. Histamine and histamine intolerance — Maintz & Novak (2007)
  3. Histamine Intolerance: The Current State of the Art — Comas-Basté et al. (2020)
  4. Low-Histamine Diets: Is the Exclusion of Foods Justified by Their Histamine Content? — Sánchez-Pérez et al. (2021)
  5. Histamine Intolerance: Symptoms, Diagnosis, and Beyond — Jochum (2024)
  6. Guideline on management of suspected adverse reactions to ingested histamine — Reese et al. (2021)