Firehouse Subs Salami
Salami is high in histamine because it is a cured, fermented meat made with red wine.
Food here is usually assembled to order from components that were prepped earlier in the day, so it tends to be fresher than a drive-through and less fresh than cooking at home. Histamine builds up as protein foods sit, so how long the chicken or beef has been in the warmer matters as much as what is in the bowl. Treat the rating above as a starting point.
This is a classic cured salami of pork and beef with salt, spices, red wine, and nitrate curing salts.
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Cured, fermented salami — the meat is fermented and cured with a lactic acid starter and sodium nitrate, which builds histamine as it ages.
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Red wine — the wine folded into the mix is high and also acts as a DAO blocker, which can make the effect more noticeable.
A fresh, uncured protein on the same menu is a far gentler choice.
This rating comes from Firehouse Subs' own published ingredient statement, read on August 11, 2026. Restaurant recipes vary by location and change over time, so always check the current listing: source 1, source 2. How we rate foods →
Firehouse Subs Salami and Firehouse Subs are trademarks of their respective owners. This page is an independent histamine reference and is not affiliated with, endorsed by, or sponsored by the brand.
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For educational purposes only. Not medical advice. Consult a healthcare professional for personal guidance.
References
- SIGHI Food Compatibility List — SIGHI (2026)
- Histamine and histamine intolerance — Maintz & Novak (2007)
- Histamine Intolerance: The Current State of the Art — Comas-Basté et al. (2020)
- Low-Histamine Diets: Is the Exclusion of Foods Justified by Their Histamine Content? — Sánchez-Pérez et al. (2021)
- Histamine Intolerance: Symptoms, Diagnosis, and Beyond — Jochum (2024)
- Guideline on management of suspected adverse reactions to ingested histamine — Reese et al. (2021)