Histamine Tracker
Red wine
Red wine is one of the most histamine-heavy drinks — fermentation builds histamine, and alcohol may interfere with the enzyme that clears it.
Red wine is often described as a double challenge: the fermentation process produces histamine directly, and the alcohol in it may slow the enzyme your body uses to break histamine down.
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Higher than white wine — red wine is consistently documented as containing more histamine than white wine; this difference is well-established across major references, though the precise reasons relate to differences in production method and grape variety rather than any single clearly established factor
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Sulfites and other compounds — red wine also contains sulfites and other biogenic amines that may stack on top of histamine, making reactions more likely even at smaller amounts
White wine or certain low-histamine wines may be worth exploring if you still want to enjoy a glass occasionally.
Track your reactions to red wine in Histamine Tracker. Log meals and symptoms to spot the patterns that matter for your body.
For educational purposes only. Not medical advice. Consult a healthcare professional for personal guidance.
References
- SIGHI Food Compatibility List — SIGHI (2026)
- Histamine and histamine intolerance — Maintz & Novak (2007)
- Histamine Intolerance: The Current State of the Art — Comas-Basté et al. (2020)
- Low-Histamine Diets: Is the Exclusion of Foods Justified by Their Histamine Content? — Sánchez-Pérez et al. (2021)
- Histamine Intolerance: Symptoms, Diagnosis, and Beyond — Jochum (2024)
- Guideline on management of suspected adverse reactions to ingested histamine — Reese et al. (2021)