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Firehouse Subs Loaded potato soup

High histamine

This potato soup is high in histamine, mainly from sour cream, bacon, and processed cheeses.

Food here is usually assembled to order from components that were prepped earlier in the day, so it tends to be fresher than a drive-through and less fresh than cooking at home. Histamine builds up as protein foods sit, so how long the chicken or beef has been in the warmer matters as much as what is in the bowl. Treat the rating above as a starting point.

This is a rich potato soup with cream, several processed cheeses, sour cream, and bacon, and that mix pushes it up.

  • Cured and cultured items lead — the bacon is cured and the sour cream is cultured, both high, and the red pepper sauce and yeast extract are high as well.

  • The cheese blend adds more — the processed cheese spread, cold pack cheese, margarine, and flour each sit at moderate, so they layer on top of the high drivers.

The potatoes and cream themselves are gentler, but the cheeses, bacon, and sauce carry the rating.

This rating comes from Firehouse Subs' own published ingredient statement, read on August 11, 2026. Restaurant recipes vary by location and change over time, so always check the current listing: source 1, source 2. How we rate foods →

Firehouse Subs Loaded potato soup and Firehouse Subs are trademarks of their respective owners. This page is an independent histamine reference and is not affiliated with, endorsed by, or sponsored by the brand.

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References

  1. SIGHI Food Compatibility List — SIGHI (2026)
  2. Histamine and histamine intolerance — Maintz & Novak (2007)
  3. Histamine Intolerance: The Current State of the Art — Comas-Basté et al. (2020)
  4. Low-Histamine Diets: Is the Exclusion of Foods Justified by Their Histamine Content? — Sánchez-Pérez et al. (2021)
  5. Histamine Intolerance: Symptoms, Diagnosis, and Beyond — Jochum (2024)
  6. Guideline on management of suspected adverse reactions to ingested histamine — Reese et al. (2021)