Is Applebee's Hot Honey Glaze High in Histamine?

Applebee's Hot Honey Glaze

High histamine

This spicy-sweet glaze is high in histamine, driven by soy sauce and white wine.

Most of this is cooked to order, which is the best case for histamine. Even so, a restaurant kitchen preps ahead and holds things warm through a service, so freshness varies more than it would at home. The rating above comes from the chain's published ingredients. If a dish is borderline for you, asking how it is prepared tells you more than the menu does.

Histamine Liberator Gluten DAO Blocker

A honey and corn syrup glaze with molasses, garlic, red jalapeno, vinegars, and a splash of wine.

Soy sauce and white wine — the soy sauce is fermented and high, and the white wine is high and a DAO blocker that can slow the enzyme that breaks histamine down.
Molasses, red jalapeno, and apple cider vinegar — these each sit in the moderate range and add to the picture, but the fermented and alcohol elements are what carry the rating.

For sweet heat without the fermented soy and wine, a simple honey drizzle is an easier choice.

This rating comes from Applebee's own published ingredient statement, read on August 11, 2026. Restaurant recipes vary by location and change over time, so always check the current listing: source 1, source 2. How we rate foods →

Applebee's Hot Honey Glaze and Applebee's are trademarks of their respective owners. This page is an independent histamine reference and is not affiliated with, endorsed by, or sponsored by the brand.