Protein powder
Protein powder varies too much by type to carry one clean answer — the base protein and the additive list are what decide it.
What "protein powder" means for histamine depends almost entirely on which powder is in the tub.
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Whey carries baggage — whey is a cheese-making byproduct, so whey concentrates can carry some histamine from that fermentation, the same reason whey powder sits on moderate lists
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Plant proteins are usually simpler — plain pea, rice, or hemp protein isn't fermented, and many people tolerate these better; soy-based powders are the exception, since textured soy protein sits high, and unflavored single-ingredient versions keep the picture clean
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The additive list matters — flavored powders often stack sweeteners, gums, and "natural flavors" that add variables for sensitive people
A plain, unflavored single-ingredient powder you already know you tolerate is the version to bake with.
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For educational purposes only. Not medical advice. Consult a healthcare professional for personal guidance.
References
- SIGHI Food Compatibility List — SIGHI (2026)
- Histamine and histamine intolerance — Maintz & Novak (2007)
- Histamine Intolerance: The Current State of the Art — Comas-Basté et al. (2020)
- Low-Histamine Diets: Is the Exclusion of Foods Justified by Their Histamine Content? — Sánchez-Pérez et al. (2021)
- Histamine Intolerance: Symptoms, Diagnosis, and Beyond — Jochum (2024)
- Guideline on management of suspected adverse reactions to ingested histamine — Reese et al. (2021)