Papa Murphy's Traditional Red Sauce
This red sauce is high, mainly because it is built on canned tomatoes.
This is sold raw and you bake it at home, which is the freshest case on this whole list. Nothing sits in a warmer, and you control how long it waits between the shop and the oven. Refrigerate it as soon as you get home and bake it the same day, because histamine builds up as protein foods sit whether that happens in a kitchen or in your fridge.
Papa Murphy's Traditional Red Sauce is high in histamine. It is built on canned tomatoes, and tomato is one of the best-known histamine liberators, meaning it can prompt your body to let go of histamine it already has stored even though the tomato itself is a fresh-tasting food.
Why papa murphy's traditional red sauce is rated high
This is the part that confuses people. Nothing in this sauce is aged, cured, or fermented, so there is no obvious culprit. The issue is that tomato works by a different mechanism than salami or aged cheese. Instead of arriving loaded with histamine, it can trigger a release of the histamine your own body is already carrying, which is why a bright, fresh-tasting sauce can still leave you feeling awful. Canned tomato is the driver that sets this sauce's level. Soybean oil sits at a moderate level and adds a little on top. The garlic, onion, olive oil, sugar and xanthan gum are not what is causing the problem here.
What changes your risk
- Canned tomato sets the level, full stop — of everything on the ingredient statement, this is the piece that puts the sauce in the high column. The rest is seasoning around it.
- Freshness does not help with a liberator — a newly opened batch of sauce is not a gentler batch. Unlike cured meat, where histamine built up over time, the tomato is a trigger from the start.
- Warm holding is not the main worry here — this sauce is low in protein, so a warming tray is a food-safety question more than a histamine one. The tomato matters far more than how long it sat.
- Soybean oil adds a moderate layer — it is the only other component rated above low, so it nudges the total up without being the cause.
- Baking does not turn a liberator off — heat does not neutralize the effect, so a baked pizza and an unbaked take-and-bake carry the same issue.
Lower-histamine alternatives
Since Papa Murphy's lets you pick your components, the lower-histamine options here are Zesty Herb Blend, Onion Mix and Chicken. Zesty Herb Blend is the closest thing to a flavor substitute if what you actually want is savory seasoning rather than tomato specifically. Onion Mix and Chicken are the other two items that sit low. There is no low-histamine tomato sauce to point you toward, because the tomato is the issue, not the recipe.
How to lower the risk
When you are building at the counter, treat Zesty Herb Blend, Onion Mix and Chicken as your low list. If you want a savory pizza without a liberator base, the herb blend is doing the job the red sauce would otherwise do. Because these are take-and-bake pizzas, you also control when it is cooked, so bake and eat it fresh rather than letting a built pizza with chicken on it sit around for a long stretch.
Common questions
Is fresh tomato sauce better than this canned-tomato one?
Not in the way people hope. Tomato is a liberator whether it is fresh or canned, so neither form is a low-histamine choice. The canned tomato in this sauce is what sets it at high.
Why is this sauce flagged when nothing in it is fermented or aged?
Because tomato does not work by carrying histamine. It works by triggering the release of histamine your body already holds, which is a separate mechanism from curing or fermenting.
Does the citric acid or vinegar taste mean it is high?
No. Sourness is not a reliable sign of histamine. The tomato is the reason this sauce rates high, not how tart it tastes.
What should I put on my pizza instead?
Zesty Herb Blend is the lower-histamine way to get savory flavor, and Onion Mix and Chicken are the other low items on this menu.
This rating comes from Papa Murphy's own published ingredient statement, read on August 10, 2026. Restaurant recipes vary by location and change over time, so always check the current listing: source 1, source 2. How we rate foods →
Papa Murphy's Traditional Red Sauce and Papa Murphy's are trademarks of their respective owners. This page is an independent histamine reference and is not affiliated with, endorsed by, or sponsored by the brand.
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For educational purposes only. Not medical advice. Consult a healthcare professional for personal guidance.
References
- SIGHI Food Compatibility List — SIGHI (2026)
- Histamine and histamine intolerance — Maintz & Novak (2007)
- Histamine Intolerance: The Current State of the Art — Comas-Basté et al. (2020)
- Low-Histamine Diets: Is the Exclusion of Foods Justified by Their Histamine Content? — Sánchez-Pérez et al. (2021)
- Histamine Intolerance: Symptoms, Diagnosis, and Beyond — Jochum (2024)
- Guideline on management of suspected adverse reactions to ingested histamine — Reese et al. (2021)