Papa Murphy's Marinara Sauce
This marinara is high because it is built on tomato and tomato puree.
This is sold raw and you bake it at home, which is the freshest case on this whole list. Nothing sits in a warmer, and you control how long it waits between the shop and the oven. Refrigerate it as soon as you get home and bake it the same day, because histamine builds up as protein foods sit whether that happens in a kitchen or in your fridge.
Papa Murphy's marinara sauce is high in histamine and carries the histamine liberator flag, because it is built on tomato and tomato puree. Tomato can prompt your body to release its own stored histamine, which is why a freshly made, cooked sauce still lands high.
Why papa murphy's marinara sauce is rated high
People get tripped up here because marinara does not look like a risky food. It is not aged, it is not cured, and it is not fermented. But tomato is one of the established liberators, and this recipe uses both tomato and concentrated tomato puree, so the liberator effect is doubled up rather than diluted. Soybean oil is also in the sauce and rates moderate on its own, which adds a little more. The dehydrated onion and garlic in the list are not the problem: they are generally low in histamine, and while some people simply do not tolerate them, that is an individual sensitivity rather than histamine release. The citric acid and calcium chloride are there for tartness and firmness, and sourness is not a reliable sign of histamine either way.
What changes your risk
- Tomato and tomato puree do it — of everything on the list, these two are the reason for the rating, and they are the base of the sauce rather than an accent.
- Freshness will not help this one — with a protein food, how it is handled can change things. A liberator works from the first bite, so a sauce made this morning is not gentler than one made yesterday.
- Soybean oil adds a little — it rates moderate on its own, so it nudges the total up rather than softening the tomato.
- Onion and garlic are not the drivers — dehydrated onion and garlic are in the sauce and are generally low in histamine. If they bother you, that is your own tolerance rather than a histamine effect.
- How long the pizza sits is a food safety question here, not a histamine one — the sauce itself is a low-protein vegetable base, so it is not the component that builds histamine while sitting. On a pizza, protein toppings are what to watch for that.
Lower-histamine alternatives
There is no lower-histamine sauce on this menu to move to, so the honest answer is that this is not a component to swap around. The lower-histamine items at Papa Murphy's are Chicken, Onion Mix, and Zesty Herb Blend. Chicken is a fresh cooked protein, and the onion and herb components add flavor without a tomato base, so building a pizza around those is where the lower territory is.
How to lower the risk
Papa Murphy's is a build-to-order counter, so the choices happen while your pizza is being assembled rather than afterward. Nothing is published as removable from the marinara itself, and on a pizza the sauce is the layer everything else sits on, so it is not something you can eat around once it is on. If you are keeping histamine down here, decide at the counter and build around the lower items we list: Chicken, Onion Mix, and Zesty Herb Blend.
Common questions
Is marinara sauce high in histamine?
Papa Murphy's marinara rates high. It is made from tomato and tomato puree, and tomato is one of the classic histamine liberators.
Does cooking tomato sauce reduce the histamine?
No. Cooking does not remove histamine, and it does not undo the liberator effect of tomato. A simmered sauce is not a lower-histamine sauce.
Why is tomato flagged when it is a fresh vegetable?
Because it is a liberator rather than a food loaded with histamine. It can trigger your body to release histamine it already has stored, so freshness does not protect you the way it does with meat or fish.
Is the garlic and onion in the marinara a problem for histamine?
They are generally low in histamine and are not what drives this rating. Some people find they do not tolerate onion or garlic, but that is individual, not histamine release.
This rating comes from Papa Murphy's own published ingredient statement, read on August 10, 2026. Restaurant recipes vary by location and change over time, so always check the current listing: source 1, source 2. How we rate foods →
Papa Murphy's Marinara Sauce and Papa Murphy's are trademarks of their respective owners. This page is an independent histamine reference and is not affiliated with, endorsed by, or sponsored by the brand.
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For educational purposes only. Not medical advice. Consult a healthcare professional for personal guidance.
References
- SIGHI Food Compatibility List — SIGHI (2026)
- Histamine and histamine intolerance — Maintz & Novak (2007)
- Histamine Intolerance: The Current State of the Art — Comas-Basté et al. (2020)
- Low-Histamine Diets: Is the Exclusion of Foods Justified by Their Histamine Content? — Sánchez-Pérez et al. (2021)
- Histamine Intolerance: Symptoms, Diagnosis, and Beyond — Jochum (2024)
- Guideline on management of suspected adverse reactions to ingested histamine — Reese et al. (2021)