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Panera Bread Five Cheese & Bacon Frittata

High histamine

This frittata is high in histamine because of the aged cheeses and smoked bacon.

Food here is usually assembled to order from components that were prepped earlier in the day, so it tends to be fresher than a drive-through and less fresh than cooking at home. Histamine builds up as protein foods sit, so how long the chicken or beef has been in the warmer matters as much as what is in the bowl. Treat the rating above as a starting point.

This is a baked egg frittata with a four-cheese souffle blend, asiago cheese, and applewood smoked bacon pieces.

  • The aged cheeses — the four cheese souffle blend and the asiago are aged cheeses, and aging builds up a lot of histamine, which drives this dish high.

  • The smoked bacon — cured and smoked pork adds to the picture, so the cheese and bacon together keep this firmly high while the eggs themselves are milder.

A cheese-free egg option would be far gentler here.

This rating comes from Panera Bread's own published ingredient statement, read on August 23, 2026. Restaurant recipes vary by location and change over time, so always check the current listing: source 1, source 2. How we rate foods →

Panera Bread Five Cheese & Bacon Frittata and Panera Bread are trademarks of their respective owners. This page is an independent histamine reference and is not affiliated with, endorsed by, or sponsored by the brand.

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References

  1. SIGHI Food Compatibility List — SIGHI (2026)
  2. Histamine and histamine intolerance — Maintz & Novak (2007)
  3. Histamine Intolerance: The Current State of the Art — Comas-Basté et al. (2020)
  4. Low-Histamine Diets: Is the Exclusion of Foods Justified by Their Histamine Content? — Sánchez-Pérez et al. (2021)
  5. Histamine Intolerance: Symptoms, Diagnosis, and Beyond — Jochum (2024)
  6. Guideline on management of suspected adverse reactions to ingested histamine — Reese et al. (2021)