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Jimmy John's Sweet n' Spicy Barbecue Sauce

High histamine

This barbecue sauce is high in histamine because of the tomato paste and pineapple juice concentrate.

Food here is usually assembled to order from components that were prepped earlier in the day, so it tends to be fresher than a drive-through and less fresh than cooking at home. Histamine builds up as protein foods sit, so how long the chicken or beef has been in the warmer matters as much as what is in the bowl. Treat the rating above as a starting point.

A tangy-spicy sauce made from corn syrup, vinegar, tomato paste, pineapple juice concentrate, molasses, and jalapeno.

  • Tomato paste — tomato is a histamine liberator and the leading high driver, so it sets the sauce's level on its own.

  • Pineapple juice concentrate, molasses, and jalapeno — pineapple is another liberator while the molasses and jalapeno sit at moderate, all keeping the sauce high.

Because the drivers are part of the recipe, leaving the sauce off is the practical fix.

This rating comes from Jimmy John's own published ingredient statement, read on August 10, 2026. Restaurant recipes vary by location and change over time, so always check the current listing: source 1, source 2. How we rate foods →

Jimmy John's Sweet n' Spicy Barbecue Sauce and Jimmy John's are trademarks of their respective owners. This page is an independent histamine reference and is not affiliated with, endorsed by, or sponsored by the brand.

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Foods With High Histamine Levels Why Freshness Matters More Than Food Lists Why Leftovers Can Trigger Histamine Symptoms What Are Histamine Liberators?

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References

  1. SIGHI Food Compatibility List — SIGHI (2026)
  2. Histamine and histamine intolerance — Maintz & Novak (2007)
  3. Histamine Intolerance: The Current State of the Art — Comas-Basté et al. (2020)
  4. Low-Histamine Diets: Is the Exclusion of Foods Justified by Their Histamine Content? — Sánchez-Pérez et al. (2021)
  5. Histamine Intolerance: Symptoms, Diagnosis, and Beyond — Jochum (2024)
  6. Guideline on management of suspected adverse reactions to ingested histamine — Reese et al. (2021)