Horseradish sauce

Horseradish itself is considered a histamine liberator — it is commonly reported to prompt a histamine response even though it doesn't contain high levels directly.

• Liberation effect — horseradish appears on histamine liberator lists in several clinical resources, and many sensitive individuals report reacting to it even in small amounts; the specific compounds responsible have not been clearly identified in the literature

• Dairy base — cream or sour cream is typically used to mellow the heat, and many people with histamine intolerance also report difficulty with dairy, which may make the combined effect more noticeable

A small amount used as a condiment rather than a sauce is likely to be more manageable than a generous serving.