Grape juice

Grapes contain naturally occurring biogenic amines, and while fresh grape juice is generally lower in histamine than wine, it still appears on many histamine intolerance lists.

• Biogenic amine content — grape juice typically contains biogenic amines (naturally occurring compounds related to histamine), which may contribute to sensitivity reactions; the histamine accumulation associated with wine is largely driven by fermentation, but fresh juice is not considered fully neutral

• Darker varieties tend to be stronger — red or purple grape juice is generally considered more problematic than white grape juice, which is often better tolerated

White grape juice or apple juice are commonly used as lower-histamine substitutes in recipes and drinks.