Is Firehouse Subs Tuna Salad High in Histamine?

Firehouse Subs Tuna Salad

High histamine

This tuna salad is high in histamine, driven by the tuna and the mayo.

Food here is usually assembled to order from components that were prepped earlier in the day, so it tends to be fresher than a drive-through and less fresh than cooking at home. Histamine builds up as protein foods sit, so how long the chicken or beef has been in the warmer matters as much as what is in the bowl. Treat the rating above as a starting point.

Histamine Liberator

It is flaked tuna mixed with mayo, cucumbers, vinegar, and seasonings.

Tuna — fish tends to run high in histamine, especially once it is canned and held, which is why tuna is a top driver here.
Mayo, vinegar, and red pepper — the mayo is high and the vinegar and diced red pepper add moderate notes, so the dressing pushes it up alongside the fish.

A freshly cooked plain beef or turkey sub on this menu tends to be a much gentler choice.

This rating comes from Firehouse Subs' own published ingredient statement, read on August 11, 2026. Restaurant recipes vary by location and change over time, so always check the current listing: source 1, source 2. How we rate foods →

Firehouse Subs Tuna Salad and Firehouse Subs are trademarks of their respective owners. This page is an independent histamine reference and is not affiliated with, endorsed by, or sponsored by the brand.