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Mayonnaise

High histamine

Mayonnaise combines vinegar and sometimes added preservatives, making it a high-caution condiment for histamine-sensitive people.

Mayo is mostly oil and egg, but the acid used for flavor and preservation is where the histamine concern often comes in.

  • Vinegar in most brands — most commercial mayonnaise contains vinegar, which is widely listed as problematic on histamine sensitivity lists; some brands use lemon juice or citric acid instead, which may be better tolerated

  • Preservatives and additives — some commercial versions include additives that people with histamine sensitivity often report reacting to, on top of the acid

Homemade mayo made with lemon juice instead of vinegar is an option some people find noticeably easier to tolerate.

Track your reactions to mayonnaise in Histamine Tracker. Log meals and symptoms to spot the patterns that matter for your body.

For educational purposes only. Not medical advice. Consult a healthcare professional for personal guidance.

References

  1. SIGHI Food Compatibility List — SIGHI (2026)
  2. Histamine and histamine intolerance — Maintz & Novak (2007)
  3. Histamine Intolerance: The Current State of the Art — Comas-Basté et al. (2020)
  4. Low-Histamine Diets: Is the Exclusion of Foods Justified by Their Histamine Content? — Sánchez-Pérez et al. (2021)
  5. Histamine Intolerance: Symptoms, Diagnosis, and Beyond — Jochum (2024)
  6. Guideline on management of suspected adverse reactions to ingested histamine — Reese et al. (2021)