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Applebee's Chipotle Lime Seasoning

High histamine

This seasoning is high in histamine, mainly from its chipotle lime blend and yeast extract.

Most of this is cooked to order, which is the best case for histamine. Even so, a restaurant kitchen preps ahead and holds things warm through a service, so freshness varies more than it would at home. The rating above comes from the chain's published ingredients. If a dish is borderline for you, asking how it is prepared tells you more than the menu does.

This is a dry rub of salt, spices, onion and garlic powder, paprika, jalapeno, and yeast extract.

  • Chipotle lime blend and yeast extract — the chipotle lime seasoning acts as a histamine liberator, and yeast extract is high on its own, so together they set the whole rub high.

  • Paprika and jalapeno — both land moderate and add to the heat-forward profile, though the two high drivers are what pin the level up.

If you want a lower-histamine plate, ask for the protein plain or with just salt and garlic instead of this rub.

This rating comes from Applebee's own published ingredient statement, read on August 11, 2026. Restaurant recipes vary by location and change over time, so always check the current listing: source 1, source 2. How we rate foods →

Applebee's Chipotle Lime Seasoning and Applebee's are trademarks of their respective owners. This page is an independent histamine reference and is not affiliated with, endorsed by, or sponsored by the brand.

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References

  1. SIGHI Food Compatibility List — SIGHI (2026)
  2. Histamine and histamine intolerance — Maintz & Novak (2007)
  3. Histamine Intolerance: The Current State of the Art — Comas-Basté et al. (2020)
  4. Low-Histamine Diets: Is the Exclusion of Foods Justified by Their Histamine Content? — Sánchez-Pérez et al. (2021)
  5. Histamine Intolerance: Symptoms, Diagnosis, and Beyond — Jochum (2024)
  6. Guideline on management of suspected adverse reactions to ingested histamine — Reese et al. (2021)