Yellow 6

Yellow 6 (Sunset Yellow FCF, E110) is rated high for histamine intolerance. It carries no histamine itself, but SIGHI rates it poorly tolerated and marks it as a possible histamine liberator.

Why yellow 6 is rated high

Yellow 6 is a synthetic azo dye that gives foods an orange-yellow color. Like tartrazine, it is one of the additives most often linked to hives and other reactions in sensitive people, and SIGHI gives it one of its strictest ratings along with a liberator mark, meaning it may prompt the body to release some of its own stored histamine.

What changes your risk

• Label names: Yellow 6, FD&C Yellow No. 6, Sunset Yellow or E110.
• Where it turns up: orange sodas, candy, cheese-flavored snacks, boxed desserts and some medications.
• Other azo dyes: people who react to Yellow 6 often react to tartrazine and Red 40 too.
• Amount: brightly colored candy and drinks carry more dye than products where it is a minor ingredient.

Lower-histamine alternatives

Undyed versions, or products colored with paprika extract, beta carotene or turmeric, avoid Yellow 6.

How to lower the risk

Scan labels on orange and yellow snacks, sodas and sweets, and ask a pharmacist about dye-free versions of medications if needed.

Common questions

Is Yellow 6 the same as Sunset Yellow?

Yes. Yellow 6, FD&C Yellow No. 6, Sunset Yellow FCF and E110 are the same dye.

Does it contain histamine?

No. It is rated high because SIGHI lists it as poorly tolerated and as a possible histamine liberator.

What natural colors can replace it?

Paprika extract, beta carotene and turmeric give similar colors and are generally well tolerated.