Panera Bread Granola
This granola is high in histamine, mainly from the sunflower seeds and pecans.
Food here is usually assembled to order from components that were prepped earlier in the day, so it tends to be fresher than a drive-through and less fresh than cooking at home. Histamine builds up as protein foods sit, so how long the chicken or beef has been in the warmer matters as much as what is in the bowl. Treat the rating above as a starting point.
This is a baked oat granola with brown sugar, butter, honey, maple syrup, pumpkin seeds, sunflower seeds, pecans, coconut, and dried cranberries.
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Seeds and nuts lead it — the sunflower seeds and pecans both run high in histamine, and they are the main reason the whole mix lands high.
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Pumpkin seeds and cranberries add to it — the pumpkin seeds and sweetened dried cranberries each sit at moderate, so more than one component keeps it up.
The oats, honey, and maple are milder, but the seed and nut mix sets the level here.
This rating comes from Panera Bread's own published ingredient statement, read on August 23, 2026. Restaurant recipes vary by location and change over time, so always check the current listing: source 1, source 2. How we rate foods →
Panera Bread Granola and Panera Bread are trademarks of their respective owners. This page is an independent histamine reference and is not affiliated with, endorsed by, or sponsored by the brand.
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For educational purposes only. Not medical advice. Consult a healthcare professional for personal guidance.
References
- SIGHI Food Compatibility List — SIGHI (2026)
- Histamine and histamine intolerance — Maintz & Novak (2007)
- Histamine Intolerance: The Current State of the Art — Comas-Basté et al. (2020)
- Low-Histamine Diets: Is the Exclusion of Foods Justified by Their Histamine Content? — Sánchez-Pérez et al. (2021)
- Histamine Intolerance: Symptoms, Diagnosis, and Beyond — Jochum (2024)
- Guideline on management of suspected adverse reactions to ingested histamine — Reese et al. (2021)