Histamine Tracker
Lettuce
Plain fresh lettuce is one of the most histamine-friendly vegetables, well-tolerated and low-risk for most people.
Lettuce doesn't contain significant histamine and isn't known to trigger histamine release or interfere with how your body breaks it down.
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Freshness is the main variable — once lettuce starts to wilt or brown, histamine can begin to accumulate, so crisp and fresh is always better
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Type matters a little — plain green lettuces like romaine and iceberg tend to be very neutral, while darker or more complex mixed greens may vary slightly
Freshly washed, crisp lettuce is about as safe a salad base as you can get.
Track your reactions to lettuce in Histamine Tracker. Log meals and symptoms to spot the patterns that matter for your body.
For educational purposes only. Not medical advice. Consult a healthcare professional for personal guidance.
References
- SIGHI Food Compatibility List — SIGHI (2026)
- Histamine and histamine intolerance — Maintz & Novak (2007)
- Histamine Intolerance: The Current State of the Art — Comas-Basté et al. (2020)
- Low-Histamine Diets: Is the Exclusion of Foods Justified by Their Histamine Content? — Sánchez-Pérez et al. (2021)
- Histamine Intolerance: Symptoms, Diagnosis, and Beyond — Jochum (2024)
- Guideline on management of suspected adverse reactions to ingested histamine — Reese et al. (2021)