Lactobacillus acidophilus

Lactobacillus acidophilus is rated moderate as a hedge, since there is no SIGHI rating for probiotic strains.

• Mixed classifications: Lists sorting probiotics into histamine-friendly and histamine-producing strains circulate widely, but they rest on limited data and place acidophilus inconsistently.

• Strain matters: Whether bacteria produce amines depends on the specific strain and conditions, so the species name alone cannot tell you much.

If you are curious about a probiotic, starting with a small amount and noting how you feel can be a practical approach.