Agave syrup

Agave sits in a gray zone — it's not a fermented or aged food, but it's flagged as moderate for histamine sensitivity.

• Observed sensitivity — many people with histamine intolerance report reacting to agave, though it's not firmly established whether this is due to histamine content, a liberation effect, or another compound in the syrup

• High fructose content — agave is very high in fructose compared to other sweeteners, and some people report digestive reactions that may overlap with histamine symptoms, though the connection isn't fully understood

If you're using agave as a "safer" sweetener, it may be worth comparing how you feel with simpler alternatives like plain white sugar, keeping in mind that individual responses to sweeteners can vary.