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Firehouse Subs Steak

High histamine

This steak filling runs high in histamine, driven by the soy protein concentrate mixed into the meat.

Food here is usually assembled to order from components that were prepped earlier in the day, so it tends to be fresher than a drive-through and less fresh than cooking at home. Histamine builds up as protein foods sit, so how long the chicken or beef has been in the warmer matters as much as what is in the bowl. Treat the rating above as a starting point.

It is thin-sliced seasoned beef bound with a few additives.

  • Soy protein concentrate — this is the main driver here, a concentrated soy ingredient that runs high in histamine and pushes the whole filling up.

  • The beef itself is milder — plain beef with salt, onion powder, and garlic powder would sit much lower, but the soy protein and starches are baked into this particular blend, so you cannot easily separate them.

On this menu, a plain roast beef or a simpler grilled option tends to be a gentler pick.

This rating comes from Firehouse Subs' own published ingredient statement, read on August 11, 2026. Restaurant recipes vary by location and change over time, so always check the current listing: source 1, source 2. How we rate foods →

Firehouse Subs Steak and Firehouse Subs are trademarks of their respective owners. This page is an independent histamine reference and is not affiliated with, endorsed by, or sponsored by the brand.

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References

  1. SIGHI Food Compatibility List — SIGHI (2026)
  2. Histamine and histamine intolerance — Maintz & Novak (2007)
  3. Histamine Intolerance: The Current State of the Art — Comas-Basté et al. (2020)
  4. Low-Histamine Diets: Is the Exclusion of Foods Justified by Their Histamine Content? — Sánchez-Pérez et al. (2021)
  5. Histamine Intolerance: Symptoms, Diagnosis, and Beyond — Jochum (2024)
  6. Guideline on management of suspected adverse reactions to ingested histamine — Reese et al. (2021)