Histamine Tracker
Cottonseed oil
A highly refined vegetable oil with no known histamine content or established links to histamine reactions.
Cottonseed oil undergoes significant refining before it's used in food, which removes most traces of the original plant's compounds.
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Heavily processed — the refining process for cottonseed oil is more extensive than many other oils, resulting in a very neutral fat with minimal plant residue
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Naturally occurring toxins removed — raw cottonseed contains gossypol, a compound removed during refining; the finished oil is considered safe for consumption and histamine-neutral
As with any oil, keeping it fresh and properly stored is the main thing to keep in mind.
Track your reactions to cottonseed oil in Histamine Tracker. Log meals and symptoms to spot the patterns that matter for your body.
For educational purposes only. Not medical advice. Consult a healthcare professional for personal guidance.
References
- SIGHI Food Compatibility List — SIGHI (2026)
- Histamine and histamine intolerance — Maintz & Novak (2007)
- Histamine Intolerance: The Current State of the Art — Comas-Basté et al. (2020)
- Low-Histamine Diets: Is the Exclusion of Foods Justified by Their Histamine Content? — Sánchez-Pérez et al. (2021)
- Histamine Intolerance: Symptoms, Diagnosis, and Beyond — Jochum (2024)
- Guideline on management of suspected adverse reactions to ingested histamine — Reese et al. (2021)