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Buffalo Wild Wings Steak

High histamine

This steak is high in histamine because of the yeast extract in its seasoning.

Most of this is cooked to order, which is the best case for histamine. Even so, a restaurant kitchen preps ahead and holds things warm through a service, so freshness varies more than it would at home. The rating above comes from the chain's published ingredients. If a dish is borderline for you, asking how it is prepared tells you more than the menu does.

This is beef sirloin with dextrose, sodium phosphate, and yeast extract.

  • Yeast extract drives it — yeast extract is a high-histamine ingredient, and it is enough to push the seasoned steak into the high range.

  • The beef is the milder part — fresh sirloin on its own is gentler, but the yeast extract in the seasoning is what sets the overall level.

A plainly seasoned protein without yeast extract would land lower.

This rating comes from Buffalo Wild Wings' own published ingredient statement, read on August 11, 2026. Restaurant recipes vary by location and change over time, so always check the current listing: source 1, source 2. How we rate foods →

Buffalo Wild Wings Steak and Buffalo Wild Wings are trademarks of their respective owners. This page is an independent histamine reference and is not affiliated with, endorsed by, or sponsored by the brand.

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References

  1. SIGHI Food Compatibility List — SIGHI (2026)
  2. Histamine and histamine intolerance — Maintz & Novak (2007)
  3. Histamine Intolerance: The Current State of the Art — Comas-Basté et al. (2020)
  4. Low-Histamine Diets: Is the Exclusion of Foods Justified by Their Histamine Content? — Sánchez-Pérez et al. (2021)
  5. Histamine Intolerance: Symptoms, Diagnosis, and Beyond — Jochum (2024)
  6. Guideline on management of suspected adverse reactions to ingested histamine — Reese et al. (2021)