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Buffalo Wild Wings Medium Sauce

Moderate histamine

This medium sauce is moderate in histamine, mainly from cayenne red pepper and soybean oil.

Most of this is cooked to order, which is the best case for histamine. Even so, a restaurant kitchen preps ahead and holds things warm through a service, so freshness varies more than it would at home. The rating above comes from the chain's published ingredients. If a dish is borderline for you, asking how it is prepared tells you more than the menu does.

Histamine Liberator

A creamy cayenne sauce made with cayenne pepper, vinegar, soybean oil, egg yolk, garlic, and spices.

  • Cayenne red pepper sets the level — it lands in the moderate range, which is the main reason this sauce reads moderate rather than low.

  • Soybean oil adds a little — it is also moderate, while the vinegar, garlic, and onion are milder background flavors.

This is one of the gentler wing sauces on the menu, with no high-histamine driver in it.

What's in it

This is a restaurant menu item, so its rating comes from its ingredients. Here is what it is typically made of and where the histamine sits. Tap any whole food for the full detail.

This rating comes from Buffalo Wild Wings' own published ingredient statement, read on August 11, 2026. Restaurant recipes vary by location and change over time, so always check the current listing: source 1, source 2. How we rate foods →

Buffalo Wild Wings Medium Sauce and Buffalo Wild Wings are trademarks of their respective owners. This page is an independent histamine reference and is not affiliated with, endorsed by, or sponsored by the brand.

Related foods

Other moderate-histamine restaurant foods.

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Learn more

Foods With High Histamine Levels Why Freshness Matters More Than Food Lists Why Leftovers Can Trigger Histamine Symptoms What Are Histamine Liberators?

For educational purposes only. Not medical advice. Consult a healthcare professional for personal guidance.

References

  1. SIGHI Food Compatibility List — SIGHI (2026)
  2. Histamine and histamine intolerance — Maintz & Novak (2007)
  3. Histamine Intolerance: The Current State of the Art — Comas-Basté et al. (2020)
  4. Low-Histamine Diets: Is the Exclusion of Foods Justified by Their Histamine Content? — Sánchez-Pérez et al. (2021)
  5. Histamine Intolerance: Symptoms, Diagnosis, and Beyond — Jochum (2024)
  6. Guideline on management of suspected adverse reactions to ingested histamine — Reese et al. (2021)