Ascorbic acid
Ascorbic acid, or vitamin C, is low in histamine and SIGHI notes it tends to lower histamine levels.
Ascorbic acid is simply vitamin C, and SIGHI rates it as well tolerated.
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Helps lower histamine: SIGHI notes vitamin C tends to lower histamine levels, which is one reason it is often welcomed on low-histamine diets.
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A small nuance: SIGHI also mentions it as a weak inhibitor of DAO, the enzyme that breaks down histamine from food, though the amounts used as a food additive are small.
Seeing E300 on a label is generally a reassuring sign rather than a concern.
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For educational purposes only. Not medical advice. Consult a healthcare professional for personal guidance.
References
- SIGHI Food Compatibility List — SIGHI (2026)
- Histamine and histamine intolerance — Maintz & Novak (2007)
- Histamine Intolerance: The Current State of the Art — Comas-Basté et al. (2020)
- Low-Histamine Diets: Is the Exclusion of Foods Justified by Their Histamine Content? — Sánchez-Pérez et al. (2021)
- Histamine Intolerance: Symptoms, Diagnosis, and Beyond — Jochum (2024)
- Guideline on management of suspected adverse reactions to ingested histamine — Reese et al. (2021)