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Applebee's Parmesan Cheese Blend

High histamine

This cheese blend is high in histamine because it is all aged hard cheeses.

Most of this is cooked to order, which is the best case for histamine. Even so, a restaurant kitchen preps ahead and holds things warm through a service, so freshness varies more than it would at home. The rating above comes from the chain's published ingredients. If a dish is borderline for you, asking how it is prepared tells you more than the menu does.

This topping is a grated mix of romano, parmesan, and asiago, all aged hard cheeses.

  • Aged hard cheeses — the parmesan cheese blend and asiago cheese blend are both aged for a long time, which is exactly what builds up histamine, so the blend is high across the board.

  • No mild part — unlike a fresh cheese such as mozzarella, there is nothing gentle here to balance it out, since every cheese in the mix is aged.

A fresh cheese would sit much lower, so that is the direction to go if you want a milder topping.

This rating comes from Applebee's own published ingredient statement, read on August 11, 2026. Restaurant recipes vary by location and change over time, so always check the current listing: source 1, source 2. How we rate foods →

Applebee's Parmesan Cheese Blend and Applebee's are trademarks of their respective owners. This page is an independent histamine reference and is not affiliated with, endorsed by, or sponsored by the brand.

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References

  1. SIGHI Food Compatibility List — SIGHI (2026)
  2. Histamine and histamine intolerance — Maintz & Novak (2007)
  3. Histamine Intolerance: The Current State of the Art — Comas-Basté et al. (2020)
  4. Low-Histamine Diets: Is the Exclusion of Foods Justified by Their Histamine Content? — Sánchez-Pérez et al. (2021)
  5. Histamine Intolerance: Symptoms, Diagnosis, and Beyond — Jochum (2024)
  6. Guideline on management of suspected adverse reactions to ingested histamine — Reese et al. (2021)