Is Applebee's Impossible Burger High in Histamine?

Applebee's Impossible Burger

High histamine

This plant-based burger is high in histamine from soy protein concentrate and yeast extract.

Most of this is cooked to order, which is the best case for histamine. Even so, a restaurant kitchen preps ahead and holds things warm through a service, so freshness varies more than it would at home. The rating above comes from the chain's published ingredients. If a dish is borderline for you, asking how it is prepared tells you more than the menu does.

Histamine Liberator

A meatless patty made from soy protein, sunflower and coconut oils, natural flavors, and soy leghemoglobin.

Soy protein concentrate — this concentrated, heavily processed soy protein runs high, and it is the backbone of the patty so it drives the whole thing.
Yeast extract — also high and used for its savory flavor, it adds to the load alongside the soy protein.

If you tolerate meat, a fresh-cooked beef patty ordered plain tends to be an easier base than this soy-and-yeast blend.

This rating comes from Applebee's own published ingredient statement, read on August 11, 2026. Restaurant recipes vary by location and change over time, so always check the current listing: source 1, source 2. How we rate foods →

Applebee's Impossible Burger and Applebee's are trademarks of their respective owners. This page is an independent histamine reference and is not affiliated with, endorsed by, or sponsored by the brand.