← All foods / Vegetables

Spinach

High histamine

Spinach contains naturally occurring histamine and also acts as a histamine liberator, making it one of the more reactive leafy greens.

Spinach stands out from most leafy greens because it contains histamine directly and may also trigger the body to release more from its own stores.

  • Natural histamine content — spinach has measurable histamine levels even when fresh, which is unusual for a leafy vegetable and sets it apart from options like lettuce or kale

  • Cooking effect — cooking spinach doesn't reduce its histamine content, and wilted or older spinach tends to have more than very fresh leaves

Lettuce, arugula, or kale are often better-tolerated alternatives if you're looking for leafy greens.

Track your reactions to spinach in Histamine Tracker. Log meals and symptoms to spot the patterns that matter for your body.

For educational purposes only. Not medical advice. Consult a healthcare professional for personal guidance.

References

  1. SIGHI Food Compatibility List — SIGHI (2026)
  2. Histamine and histamine intolerance — Maintz & Novak (2007)
  3. Histamine Intolerance: The Current State of the Art — Comas-Basté et al. (2020)
  4. Low-Histamine Diets: Is the Exclusion of Foods Justified by Their Histamine Content? — Sánchez-Pérez et al. (2021)
  5. Histamine Intolerance: Symptoms, Diagnosis, and Beyond — Jochum (2024)
  6. Guideline on management of suspected adverse reactions to ingested histamine — Reese et al. (2021)