Histamine Tracker
Romaine lettuce
A low-histamine leafy green that's well-tolerated and doesn't trigger histamine release.
Romaine is one of the more neutral vegetables you can eat — low in histamine and not known to interfere with how your body breaks it down.
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Freshness matters — like most leafy greens, romaine is best eaten fresh; once it starts wilting, natural breakdown processes begin that can gradually increase histamine content
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Compare to other greens — romaine is generally better tolerated than spinach, which is widely listed as a concern in histamine intolerance across major sensitivity sources, making it a solid swap in salads
Fresh romaine is a reliably easy choice for most people watching their histamine load.
Track your reactions to romaine lettuce in Histamine Tracker. Log meals and symptoms to spot the patterns that matter for your body.
For educational purposes only. Not medical advice. Consult a healthcare professional for personal guidance.
References
- SIGHI Food Compatibility List — SIGHI (2026)
- Histamine and histamine intolerance — Maintz & Novak (2007)
- Histamine Intolerance: The Current State of the Art — Comas-Basté et al. (2020)
- Low-Histamine Diets: Is the Exclusion of Foods Justified by Their Histamine Content? — Sánchez-Pérez et al. (2021)
- Histamine Intolerance: Symptoms, Diagnosis, and Beyond — Jochum (2024)
- Guideline on management of suspected adverse reactions to ingested histamine — Reese et al. (2021)