Frisee lettuce
Frisee is a low-histamine salad green with no known histamine-releasing or DAO-blocking properties.
Frisee (a curly, slightly bitter chicory-family green) is a fresh vegetable that doesn't contain notable histamine and has no established mechanisms that worsen histamine reactions.
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Part of the chicory family — like escarole and endive, frisee belongs to a group of greens that are generally well-tolerated from a histamine perspective when eaten fresh
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Use it fresh — frisee wilts quickly, and as with most leafy greens, freshness helps keep biogenic amine levels as low as possible
It's a nice textural addition to salads and works well paired with other low-histamine ingredients.
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For educational purposes only. Not medical advice. Consult a healthcare professional for personal guidance.
References
- SIGHI Food Compatibility List — SIGHI (2026)
- Histamine and histamine intolerance — Maintz & Novak (2007)
- Histamine Intolerance: The Current State of the Art — Comas-Basté et al. (2020)
- Low-Histamine Diets: Is the Exclusion of Foods Justified by Their Histamine Content? — Sánchez-Pérez et al. (2021)
- Histamine Intolerance: Symptoms, Diagnosis, and Beyond — Jochum (2024)
- Guideline on management of suspected adverse reactions to ingested histamine — Reese et al. (2021)